vTrue Radiance is a physician-developed blend of 25 botanical extracts, minerals and vitamins that promote beautiful skin from within.† “VTRUE TO YOURSELF!”

vTrue’s formula naturally supports the production of collagen to help minimize fine lines and wrinkles, antioxidant protection against UV free radical damage, and radiance enhancing mirco-circualtion.† VTRUE TO YOUR HEALTH!

THE SCIENCE BEHIND VTRUE

The skin is the body’s largest organ, comprising about 15% of our body weight. The total skin surface of an adult ranges from 12 to 20 square feet. In terms of chemical composition, the skin is about 70% water and 25% protein.

Skin cells, like every human cell, require specific nutrients to function properly. Some come from food, and others are produced by the body provided it is healthy and properly nourished. Skin cells are renewed every 3-5 weeks from a deep layer called the dermis. The dermis is made of a dense mesh-work of collagen and elastin fibers.

Collagen is the primary support structure of the skin, accounting for seventy-five percent of its tissue and about 90 percent of its thickness. The dermis receives nutrients from capillaries (tiny blood vessels), that are important for oxygenating and nourishing the skin. Collagen and elastin deteriorate with age and sun exposure, resulting in wrinkles and facial sag. The result is the development of dry, wrinkled skin that has lost much of its inherent strength and elasticity.

The dermis is the layer responsible for the skin’s structural integrity, elasticity and resilience. Wrinkles arise and develop in the dermis. There­fore, an anti-wrinkle treatment has a chance to succeed only if it can reach as deep as the der­mis. Both collagen and elastin are critically im­portant skin proteins: Collagen provides the skin with strength and suppleness, as well as an in­herent ability to retain moisture; and elastin pro­vides the skin’s resilience and elasticity. The key type of cell in the dermis is the fibroblast, which synthesizes collagen, elastin and other structur­al molecules. The proper function of fibroblasts is highly important for overall skin health.

Topical creams that contain collagen and elastin, typically never reach the dermis because collagen and elastin molecules are too large to penetrate the epidermis. Hence, contrary to what some manufacturers of these creams might imply, they mostly have little effect on skin wrinkles. Many nutritional molecules in skin care products actually work when taken internally; thus, the quality of the nutrients delivered to the dermis depends on what you’ve eaten, or taken as a supplement. vTrue contains multiple nutrients that have shown substantive efficacy in the facilitation of collagen and elastin production.

Another key mechanism of the aging process is free radical damage. The skin is a major target for toxic insult by a broad spectrum of physical (i.e. UV radiation) and chemical agents that are capable of degrading its structure and function. Many environmental pol­lutants are either themselves oxidants or catalyze the production of reactive oxygen species (ROS) directly or indirectly. Skin is a major target of oxi­dative stress due to reactive oxygen species (ROS) that originate in the environment and in the skin itself.

Antioxidants attenuate the damaging effects of ROS and can impair and/or reverse many of the events that contribute to epidermal toxicity and disease. Increased or prolonged free radical action can overwhelm ROS defense mechanisms, contributing to the development of cutaneous dis­eases and disorders such as skin cancer.

One approach to preventing or treating these ROS-mediated disorders is based on the administra­tion of various antioxidants in an effort to restore homeostasis. The antioxidants contained in vTrue have shown substantive efficacy in cell culture systems and in animal models of oxidant injury.